Analysis of 5-year clinical and radiological outcomes in patients with psoriatic arthritis observed as part of the Treat to target strategy. Preliminary data

Objective : to analyze preliminary data on 5-year clinical and radiographic outcomes in patients with early psoriatic arthritis (PsA) observed as part of the Treat target (T2T) strategy. Patients methods . We examined 37 (18 men 19 women) PsA who met CASPAR criteria (2006), received treatment according principles T2T strategy for 24 months. The mean age was 43.3±11.7 years, median (Me) duration 72 [60; 90] months, psoriasis – 120 [88; 180] follow up 62 [51; 81] After completion participation strategy, were followed a real setting. Most used methotrexate, biologic disease modifying antirheumatic drugs non-steroidal anti-inflammatory drugs. In dynamics after 5 activity determined by DAPSA index achievement minimum (MiDA). 16 (43%) patients, dynamic assessment changes joints hands feet performed using Sharp quantitative method modified (m-Sharp/vanderHeijde). Results discussion By months therapy (the end study), remission registered (52%) same number cases (16%) low (LDA), moderate (MDA) high (HDA) noted. Me 3.85 [0.67; 21.76], MiDA detected 22 (59.5%) patients. years observation, 7.67 [2.2; 14.5]. Remissions achieved 13 (35%) LDA also (35%), MDA (14%), HDA remained 6 (16%), 20 (54%). No significant differences found when comparing at (at study) follow-up (p=0.41). 11 (69%) out negative trend recorded radiological progression. Conclusion follow-up, 70% treated an stage or LDA, 54% MiDA. 69% despite MiDA, there feet.